Porcine rotavirus B (PRV-B) is a double-stranded RNA viruses roughly 3.3 kb in length. PRV-B belongs to the family Reoviridae, Sedoreovirinae subfamily, and Rotavirus genus. First identified in 1973, rotaviruses cause acute viral gastroenteritis in young animals and children. A recent study has demonstrated PRV-B to be a primary causative agent of diarrhea outbreaks in newborn piglets. Previously, co-infection with PRV-A and PRV-C have made the role of PRV-B unclear.