Porcine Deltacoronavirus (PDCoV) is an enveloped, single-stranded, positive-sense RNA virus with a genome of appropriately 25 kb in length belonging to the genus Deltacoronavirus of the family Coronaviridae. Porcine deltacoronavirus was first detected in pig samples collected in 2009 in Hong Kong during a molecular surveillance study. In February 2014, emergence of PDCoV in U.S. swine was reported and the virus rapidly spread to multiple U.S. states. Since then, PDCoV has been detected in multiple other countries such as South Korea, Canada, China, Vietnam and Japan. PDCoV infection can be fatal in nursing piglets but sows often do not display clinical signs. Symptoms include acute diarrhea, vomiting, dehydration, and intestinal lesions.